O przedmiocie

PAO PEREIRA TINCTURE

(tinctura Geissospermum vellosii)

Pao Pereira is an indigenous tree from the Amazon rainforest.

It is used as an alternative therapy for many cancers; alone or in combination with cancer drugs. The extract from the bitter inner-bark, seems to effectively suppress the proliferation of HIV, herpes viruses, cancer and leukemia cells.

It is effective in preventing among others, prostate cancer and/or reducing PSA levels*.

Used in the treatment and prevention (prophylaxis) of malaria (Plasmodium falciparum**); to boost the immune system. It can also be useful in combating AIDS and herpes.

The alkaloids from Pao Pereira (family Apocynaceae), have the same toxic effect against certain cancer cells; however with no such effect on normal ones.

Pao Pereira also inhibits replication of the Herpes simplex virus genome.

It crosses the blood-brain barrier easily and attaches itself to potential cancer cells.

Brain cancer is very difficult to treat; glioblastoma is the most common and aggressive brain tumor.

The alkaloids carry a risk of toxicity only in cases of overdose and have no known side effects.

The tincture can be applied to all types of disease involving immunodeficiency(prevents the body from fighting infections and diseases) and can be used as a synergistic adjunct therapy; alongside chemo- and radiotherapy in many forms of cancer.

Constituents

Indole and beta-carboline alkaloids: geissospermine, flavopereirine, dihydroflavopereirine, vellosine, geissoschizoline (and derivatives), geissoschizoline N4-oxide, 1,2-dehydrogeissoschizoline, apogeissoschizine and pausperadine.

Pharmacology

Alkaloids from the inner bark of Geissospermum vellosii (Geissospermun laeve) possess a variety of therapeutic properties including antimalarial activities, activity as a natural sexual stimulant and inhibition of the proliferation of HIVand herpes viruses.

Extract from the bark can be used to treat intermittent fevers. Geissospermum species are believed to purify the blood and the liver. These species are said also to be used for the prevention (prophylaxis) of malaria.

Bark extracts of Geissospermum vellosii, enriched in alpha-carboline alkaloids have significant anticancer activities and in certain preclinical models they suppress prostate cancer cells.

Flavopereirine*** exerts a selective inhibition action on viral HIV infection, particularly in patients infected by HIV-1; providing a method for the treatment of Human Immunodeficiency Virus.

It shows also promise for treating low-grade prostate cancer and preventing the onset of metastatic disease**** and/or reducing the doubling time of PSA levels in men with positive biopsies; showing relatively low Gleason scores and morphologies characteristic of non-invasive, slow-progressing prostate cancer.

Applied to a line of cultured cancer cells, the extract significantly and fast suppressed cell growth; it caused cancer cells to die. It also caused a significant decrease in overall tumor size. Research also suggested that, since Pao pereira has tumor-suppressing activity without toxicity, it can be used to preventcancer; not just as a treatment for it.

The greatest effect on tumor growth seems to occur at lower doses of the Pao Pereira.

The lack of an effective therapy is a major problem with the treatment of pancreatic cancer; this is one of the most lethal types of cancer.

An extract of Pao Pereira (Pao), was investigated for its anti-pancreatic cancer effect. Alone or in combination with the first-line chemotherapeutic drug Gemcitabine, brand name Gemzar® (Gem), the current standard of care for advanced pancreatic cancer. While Gem did not provide significant inhibition, Pao treatment significantly suppressed tumor growth in mice by 70-72%.

Combined Pao and Gem treatment further enhanced the tumor inhibitory effect compared to Gemcitabine alone and markedly reduced metastatic lesions in the peritoneum (membrane lining the abdominal cavity and covering abdominal organs).

Combining Pao Pereira with chemotherapy drugs (Carboplatin) also seems to have synergy of action on ovarian cancer cells.

Pao pereira alone suppressed tumor growth by 79% and decreased volume of ascites by 55%. When combined with carboplatin (Paraplatin®), tumor inhibition reached 97% and ascites (abdominal dropsy) was completely eradicated.

http://www.naturallivingcenter.net/ns/DisplayMonograph.asp?StoreID=b571dewxvcs92jj200akhmccqa7w8v75&DocID=bottomline-paopereira

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